The deuteragonist of the Naruto series, Sasuke Uchiha, is one of the most powerful characters in the series. Boruto Age too. He stands as tall as the other Hokage of Konoha, supporting Naruto Uzumaki from the shadows and protecting the village from dangers that Naruto cannot see. Sasuke is an incredibly powerful ninja, considered the strongest in the world along with Naruto Uzumaki. As such, he holds a number of powerful abilities up his sleeve, some of which can do devastating damage.
Until recently, Sasuke had access to his Rinnegan, which gave him a wide range of techniques to use in battle. Now that he has lost this power, his strongest jutsu arsenal has changed dramatically. in Boruto: Two Blue VortexesSasuke's strongest jutsu is a unique technique that can cause devastating damage to his enemies, even though he no longer has the Rinnegan. This jutsu is the Kagutsuchi Chidori, which he can still use, especially in combination with his full-body Susanoo, making it one of the most powerful techniques in existence in the world. Boruto.
Sasuke Uchiha losing his Rinnegan means Full Body Susanoo Kagutsuchi Chidori is his strongest jutsu
Sasuke Uchiha awakens the power of the Rinnegan in Naruto Chapter 674, which was released on May 12, 2014 in Shueisha's Weekly Shonen Jump issues #22-23. In this same chapter, Sasuke was given half of the Sage's power, and thus, he gained access to the Sixen. With it, he can manipulate gravitational forces, absorb chakra, use various summons, and gain complete control over life and death, among other things.
In the Boruto series, he was greatly angered by Sasuke for not using his Rinnegan properly. However, he has now completely lost his Rinnegan, meaning that his true superpowers are no longer accessible to him. When it comes to his current strongest jutsu, Sasuke has the Kagutsuchi Chidoriwhich he first used in Naruto Chapter 698 November 17, 2014, in Shueisha's Weekly Shōnen Jump Issue #49. To demonstrate this technique, Sasuke combined the power of his Blaze Release: Kagutsuchi with the Lightning Release Chidori. Using these powers together greatly increased his offensive output, and his Chidori became strong enough to rip through even the six path extended Rasengan. This jutsu was so strong that it completely blew off Naruto's arm and caused devastating damage to Sasuke himself.
“So here it comes. I'm going to use Kagutsuchi with Chidori and settle it with one attack.” – Sasuke before using Kagutsuchi Chidori, Naruto Chapter #698
Now, as an adult, Sasuke has superior control over not only this jutsu but also other mangekyo abilities such as Susanoo. As such, the combination of Full Body Susanoo and Kagutsuchi Chidori should be possible for him, which would give birth to his new strongest jutsu after 12 years.

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Why Sasuke's New Strongest Jutsu Is Still Powerful Enough To Take Down Otsutsuki Level Ninjas
Kagutsuchi Chidori is one of the most underrated jutsu in the Naruto universe. This technique, despite the small chakra, was capable of damaging six path-level individuals at the time. However, since then, Sasuke Uchiha has grown considerably in terms of power. His control over nature changes has improved dramatically, and his Mangekyo Sharingan use is even better than before. Putting two and two together, Sasuke's Kagutsuchi Chidori is now even better than before, and what's more, he can now combine this jutsu with his Susanoo as well. There's no reason to believe that Sasuke can't do that, as he's already shown the use of the Susanoo Chidori in Chapter 695 of Naruto.
“I'm sorry, Boruto. It was my responsibility as your teacher to stop Momoshiki's strike, but I couldn't be there for you when you needed me. There's no need for the village to hate anyone but me.” — Sasuke Uchiha is ready to take on new challenges, Boruto: Naruto the Next Generation Chapter #69
By combining the Kagutsuchi with it, Sasuke could create a devastating technique that should in theory be able to take down even Otsutsuki-level ninjas. The only problem is that Otsutsuki is strong enough to absorb any ninjutsu-based abilities. That's why this technique should only be launched at the last minute before being absorbed, and if they hit, they can easily take down Otsutsuki in a single strike. This is especially true when one looks at Sasuke's overall power level in Boruto: Two Blue Vortexes. After a three-year timeskip, Sasuke is stronger than ever, even though he lost his greatest asset, officially losing his Rinnegan in Chapter 53 of Boruto: Naruto Next Generation on December 20, 2020.
Sasuke has trained his mind and body in such a way that he is stronger than ever. On December 20, 2023, in Boruto: Two Blue Vortex Chapter 5, during his battle against the Code, Sasuke was shown to be strong enough to have one of his eyes taken from him. The code is stronger than Jigen, whom Sasuke struggles with in battle despite becoming a Rinnegan in Boruto: Naruto Next Generation Chapter 38. Clearly, he's on a completely different level now. As such, his control over unique powers like Kagutsuchi Chidori and Susanoo is going to be on a completely different level.
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Code: Uchiha, you!!! How dare you catch my eye?
Sasuke: Listen closely, Boruto! There is no way we can win against him now. So run away. Survive by all means and build on the skills I've thrown at you. Then no one can stop you.
– An exchange between Sasuke and Kod, which shows that the former has become stronger, Boruto: Two Blue Vortex Chapter #5
Sasuke Uchiha has more major upgrades to Boruto: two Blue Vortexes
Boruto: Two Blue Vortex lined up even more significant upgrades for Sasuke Uchiha. The very first of these upgrades was teased in the Boruto Volume release, and repeated in Boruto: Two Blue Vortex Volume #8, where it was stated that Sasuke Uchiha trained his mind and body with Boruto Uzumaki. Later down the line, it was also confirmed Boruto: Two Blue Vortexes Chapter 28 that Sasuke's sword was upgraded by Sumire, and his chakra was registered to it, meaning that this new, sharper, stronger and better blade could be wielded by the Uchiha, which also increased his overall power.
“The blade has been reshaped from its original material to maximize its strength. Not only that, but your Uchiha-style kenjutsu Hagoromo will hold onto itself once you grip the hilt.” — Sumire Sasuke's Sword, Two Blue Vortex explains the upgrades in Chapter #28.
On top of that, Sasuke is probably going to get a significant buff to his base form now that he no longer has the Rinnegan. Immediately after Sasuke's return, possibly at the end of the Hidari arc, which has already begun in the Two Blue Vortex manga, it is likely that Sasuke will be seen reaching a completely new power. We can't wait for Mikio Ikemoto and Masashi Kishimoto to demonstrate that. Perhaps in his upcoming battles in the Boruto series, he's going to unleash the power of his Susanoo: Kagutsuchi Chidori and show fans why, despite being out of his prime, he's still among the strongest in the world.
The latest chapter of Boruto: Two Blue Vortex by Mikio Ikemoto and Masashi Kishimoto is available to read through Manga Plus and Viz Media.